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It’s necessary to monitor for any changes in signs and to discuss them with a healthcare skilled for applicable management. Sure, tesamorelin is legal to be used with a prescription in the Usa, primarily for treating HIV-related extra abdominal fats. Tesamorelin and Sermorelin are both artificial two peptides designed to stimulate the release of progress hormone (GH) by mimicking the effects of growth hormone-releasing hormone (GHRH).
Additionally, I’ll provide more info on how it’s typically dosed and reveal what a typical cycle of it appears like for therapeutic uses. Not all the time — but depending on the peptide, your targets, and your sensitivity to GH, cycling may help forestall tolerance and optimize results. An intriguing side of Tesamorelin lies in its structural modification on the N-terminus, diverging from natural GHRH.
“The three randomized-controlled trials have proven that Tesamorelin is a secure and efficient treatment for lipodystrophy in HIV patients. If you are a person who is 20% body fat or greater, your results won’t be as noticeable as someone who has significantly less body fats upon initiation of Tesamorelin. Moreover, the Tesamorelin peptide can do all of this with out negatively affecting your glucose ranges (i.e. it does NOT induce insulin resistance). Whereas you do want triglycerides to provide your body with power, having too many triglycerides in your blood can increase your threat of heart illness.
This consists of reaching the essential deep sleep levels, the place the body undergoes essential restore and regeneration processes. To meet development hormone (GH) deficiency in your kids, seek the guidance of your doctor for an effective prescription. As mentioned earlier, one of many major symptoms of HIV and antiretroviral treatment is lipodystrophy. 5 It refers to both excessive build-up of fat in certain areas of the body, especially the belly area, or loss of normal body fats.
CD-36 receptors, which are often found in fats cells, immune cells, and liver tissue, promote cardiovascular advantages upon binding to Hexarelin. Once bounded, Ipamorelin triggers a biochemical cascade that releases progress hormone from the pituitary gland into the bloodstream. They work synergistically with development hormone-releasing hormone (GHRH), leading to a lift in plasma GH ranges even at low doses.
Studies present investigating both together might give fuller metabolic profiles and fats distribution information than testing brokers in isolation. This might be a strong platform to check central adipose dynamics and progress issue interaction in preclinical adipocyte fashions. Tesamorelin and https://poptop.online/read-blog/14411_combined-therapies-sermorelin-with-ipamorelin.html are two peptides that have been studied for growth hormone launch in research settings. Ipamorelin is a human-made peptide from the growth hormone-releasing peptide family. Tesamorelin has proven promise for concentrating on extra belly fat in experimental fashions of sure metabolic conditions.
Sermorelin increases GH ranges with peak levels occurring about 30 minutes to some hours after administration. Research report GH will increase ranging from 2 to 10 instances baseline ranges following Sermorelin administration, with once-daily administration resulting in lower finish increases. Sermorelin promotes a pure, pulsatile release of GH, mimicking the physique’s natural GH secretion pattern, which helps avoid off-target results.
Progress hormone plays a vital role in regulating various metabolic processes, together with protein synthesis and tissue restore, that are essential for muscle progress. Subsequently, by selling the secretion of progress hormone, tesamorelin can contribute to the enhancement of muscle mass and energy. Nevertheless, its direct results on immune cells is probably not vital, as its main function is related to metabolic regulation somewhat than immune system modulation. Ipamorelin and Sermorelin are both peptides designed to stimulate the discharge of development hormone, however they operate through different mechanisms. In distinction, Sermorelin is an analog of development hormone-releasing hormone (GHRH). It mimics the pure GHRH produced by the hypothalamus, thereby stimulating the pituitary gland to launch progress hormone.
A fastened bedtime, a darkish room, and a 60 to 90 minute wind down window
shield your pulses and your results. This muscle-building potential can result in improved bodily performance, elevated muscle definition, and greater
overall power. As individuals age, the natural manufacturing
of HGH decreases, which might result in visible signs of aging similar to wrinkles, decreased pores and skin elasticity, and an general loss
of youthful look 4.
Peptides—short chains of amino acids—are more and more
in style in performance, health, and regenerative drugs worlds.
Instead of using a single peptide, some practitioners use peptide stacks, combining multiple peptides to
amplify results on fats loss, muscle development, restoration, and even anti-aging or cognitive assist.
• Sermorelin is an artificial analog of the primary 29 amino acids of growth hormone-releasing hormone (GHRH).
I’ve personally experienced an improvement in my focus and mental clarity since beginning this peptide therapy.
These cognitive benefits can contribute to an general sense
of vitality and improved high quality of life. Many of
my clients report feeling extra refreshed upon waking and experiencing improved daytime vitality levels.
I’ve observed this impact in my own sleep patterns as properly, finding
that I get up feeling more rested and alert.
For a full breakdown of the differences between GHRP-6 and GHRP-2, together with finest stacking protocols and
use circumstances, see our detailed guide. To go deeper, this free peptide cheat
sheet incorporates everything you need to find out about selecting the best peptides for your
objectives and different highly effective small molecules you
should find out about. Start with 2 peptides most, set
up tolerance and benefits, then think about including a 3rd solely
after additional analysis. The “biochemical gamble” of extreme stacking can lead
to unpredictable interactions, receptor competitors, and problem troubleshooting opposed effects.
Stacking enhances advantages beyond what single compounds can achieve and
also helps offset unwanted effects. As far as I can inform, here are the most popular
doses for each peptide in each stack.
The information shouldn’t be thought-about complete
and should not be used rather than a visit, phone or telemedicine name, consultation or recommendation of your doctor
or other healthcare provider. Only a qualified doctor in your state
can determine should you qualify for and should undertake
treatment. To understand how the CJC-1295 and Ipamorelin stack compares to other
popular growth hormone-releasing agents, here’s a breakdown of key options—including their mechanisms, benefits,
and risks. sermorelin vs ipamorelin cjc stack remedy provides the potential to reverse or mitigate these results.
By growing HGH, it could aid in reducing the appearance of wrinkles, enhancing skin elasticity, and rejuvenating one’s total
youthful appearance. Some users of CJC 1295 have reported experiencing
higher sleep high quality because of its remedy.
Another notable software of CJC 1295 is within the realm of restoration. Its affect on tissue restore and regeneration can expedite the healing course of from injuries or
intense physical actions. Elevated HGH levels play a critical function in promoting the
development and repair of muscle tissues. This
increase in HGH ranges can contribute to the discount of
wrinkles, enhanced pores and skin elasticity, and the restoration of
a younger and vibrant look.
For example, mouse models of sarcopenia (muscle wasting) or diet-induced obesity are common. Scientists
monitor modifications in lean mass, fat mass distribution, bone mineral density, and glucose tolerance over weeks or
months. Rodent models enable for bigger pattern sizes
and the technology of intensive information, which is key to establishing a broad
cjc 1295 ipamorelin security profile. Actual
Peptides ensures that our compounds, such as Semax Amidate
Peptide, are high-purity for constant leads to these sensitive
fashions. Researchers trying to answer what is cjc 1295 ipamorelin and totally understand
its effects make the most of a variety of laboratory fashions, every designed to isolate particular biological outcomes.
The choice of mannequin is determined by the research question,
shifting from easy cellular studies to complicated, living systems.
Potential benefits embody improved muscle restore, enhanced metabolism, physique composition assist, and
regenerative effects without direct hormone substitute.
Sermorelin’s major operate is to extend HGH production, nevertheless it does much more inside the physique.
As Soon As HGH ranges rise, the hormone stimulates cell regeneration, improves metabolism,
and helps tissue repair. This, in flip, results in improved muscle mass, higher pores and
skin elasticity, elevated power ranges, and enhanced general vitality.
Sermorelin remedy helps the body’s ability to rejuvenate itself by boosting natural
HGH production. It’s not a steroid, not a SARM, and never
synthetic progress hormone — it’s a selective peptide that works together with your body’s own rhythm to optimize GH ranges safely and constantly.
I’ve personally experienced sooner recovery instances between workouts since incorporating this peptide combination into my routine.
Athletes and bodybuilders I work with often report
noticeable enhancements in muscle fullness
and recovery instances within the first month of use.
Particular Person goals and medical steering should determine the choice between these peptides based mostly
on desired results and potential benefits.
For Ipamorelin, dosages normally range from a hundred to 300 mcg per dose, and it’s
often administered 2-3 times a day. It’s important to notice that these peptides should solely be used beneath the supervision of a medical professional,
as incorrect dosing can lead to potential
unwanted facet effects or lowered effectiveness. The purity of the research materials is an oblique
but crucial security consideration. An impure compound could lead to toxic cjc
1295 ipamorelin unwanted effects which may be mistakenly attributed to
the peptides themselves.
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Apart from one Fangoria interview in 1990, Curry by no means publicly acknowledged his involvement in It till an interview with Moviefone in 2015, the place he referred to as the function of Pennywise “an exquisite part”. He rose to prominence as Dr. Frank-N-Furter in the musical movie The Rocky Horror Image Show (1975), reprising the role he had originated within the 1973 London, 1974 L A, and 1975 Broadway musical stage productions of The Rocky Horror Show. Grant Thornton LLP is a licensed impartial CPA firm that gives attest providers to its shoppers, and Grant Thornton Advisors LLC and its subsidiary entities present tax and business consulting services to their clients. Grant Thornton Advisors LLC and its subsidiary entities usually are not licensed CPA companies. If you imagine that a judge has a disability affecting his or her efficiency or has violated a quantity of of the Canons of the Code of Judicial Conduct, it is applicable to file a complaint with the CJC. Please describe as particularly as potential what the decide did or stated that causes you to believe she or he has a disability or has committed misconduct.
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It’s necessary to monitor for any changes in signs and to discuss them with a healthcare skilled for applicable management. Sure, tesamorelin is legal to be used with a prescription in the Usa, primarily for treating HIV-related extra abdominal fats. Tesamorelin and Sermorelin are both artificial two peptides designed to stimulate the release of progress hormone (GH) by mimicking the effects of growth hormone-releasing hormone (GHRH).
Additionally, I’ll provide more info on how it’s typically dosed and reveal what a typical cycle of it appears like for therapeutic uses. Not all the time — but depending on the peptide, your targets, and your sensitivity to GH, cycling may help forestall tolerance and optimize results. An intriguing side of Tesamorelin lies in its structural modification on the N-terminus, diverging from natural GHRH.
“The three randomized-controlled trials have proven that Tesamorelin is a secure and efficient treatment for lipodystrophy in HIV patients. If you are a person who is 20% body fat or greater, your results won’t be as noticeable as someone who has significantly less body fats upon initiation of Tesamorelin. Moreover, the Tesamorelin peptide can do all of this with out negatively affecting your glucose ranges (i.e. it does NOT induce insulin resistance). Whereas you do want triglycerides to provide your body with power, having too many triglycerides in your blood can increase your threat of heart illness.
This consists of reaching the essential deep sleep levels, the place the body undergoes essential restore and regeneration processes. To meet development hormone (GH) deficiency in your kids, seek the guidance of your doctor for an effective prescription. As mentioned earlier, one of many major symptoms of HIV and antiretroviral treatment is lipodystrophy. 5 It refers to both excessive build-up of fat in certain areas of the body, especially the belly area, or loss of normal body fats.
CD-36 receptors, which are often found in fats cells, immune cells, and liver tissue, promote cardiovascular advantages upon binding to Hexarelin. Once bounded, Ipamorelin triggers a biochemical cascade that releases progress hormone from the pituitary gland into the bloodstream. They work synergistically with development hormone-releasing hormone (GHRH), leading to a lift in plasma GH ranges even at low doses.
Studies present investigating both together might give fuller metabolic profiles and fats distribution information than testing brokers in isolation. This might be a strong platform to check central adipose dynamics and progress issue interaction in preclinical adipocyte fashions. Tesamorelin and https://poptop.online/read-blog/14411_combined-therapies-sermorelin-with-ipamorelin.html are two peptides that have been studied for growth hormone launch in research settings. Ipamorelin is a human-made peptide from the growth hormone-releasing peptide family. Tesamorelin has proven promise for concentrating on extra belly fat in experimental fashions of sure metabolic conditions.
Sermorelin increases GH ranges with peak levels occurring about 30 minutes to some hours after administration. Research report GH will increase ranging from 2 to 10 instances baseline ranges following Sermorelin administration, with once-daily administration resulting in lower finish increases. Sermorelin promotes a pure, pulsatile release of GH, mimicking the physique’s natural GH secretion pattern, which helps avoid off-target results.
Progress hormone plays a vital role in regulating various metabolic processes, together with protein synthesis and tissue restore, that are essential for muscle progress. Subsequently, by selling the secretion of progress hormone, tesamorelin can contribute to the enhancement of muscle mass and energy. Nevertheless, its direct results on immune cells is probably not vital, as its main function is related to metabolic regulation somewhat than immune system modulation. Ipamorelin and Sermorelin are both peptides designed to stimulate the discharge of development hormone, however they operate through different mechanisms. In distinction, Sermorelin is an analog of development hormone-releasing hormone (GHRH). It mimics the pure GHRH produced by the hypothalamus, thereby stimulating the pituitary gland to launch progress hormone.
A fastened bedtime, a darkish room, and a 60 to 90 minute wind down window
shield your pulses and your results. This muscle-building potential can result in improved bodily performance, elevated muscle definition, and greater
overall power. As individuals age, the natural manufacturing
of HGH decreases, which might result in visible signs of aging similar to wrinkles, decreased pores and skin elasticity, and an general loss
of youthful look 4.
Peptides—short chains of amino acids—are more and more
in style in performance, health, and regenerative drugs worlds.
Instead of using a single peptide, some practitioners use peptide stacks, combining multiple peptides to
amplify results on fats loss, muscle development, restoration, and even anti-aging or cognitive assist.
• Sermorelin is an artificial analog of the primary 29 amino acids of growth hormone-releasing hormone (GHRH).
I’ve personally experienced an improvement in my focus and mental clarity since beginning this peptide therapy.
These cognitive benefits can contribute to an general sense
of vitality and improved high quality of life. Many of
my clients report feeling extra refreshed upon waking and experiencing improved daytime vitality levels.
I’ve observed this impact in my own sleep patterns as properly, finding
that I get up feeling more rested and alert.
For a full breakdown of the differences between GHRP-6 and GHRP-2, together with finest stacking protocols and
use circumstances, see our detailed guide. To go deeper, this free peptide cheat
sheet incorporates everything you need to find out about selecting the best peptides for your
objectives and different highly effective small molecules you
should find out about. Start with 2 peptides most, set
up tolerance and benefits, then think about including a 3rd solely
after additional analysis. The “biochemical gamble” of extreme stacking can lead
to unpredictable interactions, receptor competitors, and problem troubleshooting opposed effects.
Stacking enhances advantages beyond what single compounds can achieve and
also helps offset unwanted effects. As far as I can inform, here are the most popular
doses for each peptide in each stack.
The information shouldn’t be thought-about complete
and should not be used rather than a visit, phone or telemedicine name, consultation or recommendation of your doctor
or other healthcare provider. Only a qualified doctor in your state
can determine should you qualify for and should undertake
treatment. To understand how the CJC-1295 and Ipamorelin stack compares to other
popular growth hormone-releasing agents, here’s a breakdown of key options—including their mechanisms, benefits,
and risks.
sermorelin vs ipamorelin cjc stack remedy provides the potential to reverse or mitigate these results.
By growing HGH, it could aid in reducing the appearance of wrinkles, enhancing skin elasticity, and rejuvenating one’s total
youthful appearance. Some users of CJC 1295 have reported experiencing
higher sleep high quality because of its remedy.
Another notable software of CJC 1295 is within the realm of restoration. Its affect on tissue restore and regeneration can expedite the healing course of from injuries or
intense physical actions. Elevated HGH levels play a critical function in promoting the
development and repair of muscle tissues. This
increase in HGH ranges can contribute to the discount of
wrinkles, enhanced pores and skin elasticity, and the restoration of
a younger and vibrant look.
For example, mouse models of sarcopenia (muscle wasting) or diet-induced obesity are common. Scientists
monitor modifications in lean mass, fat mass distribution, bone mineral density, and glucose tolerance over weeks or
months. Rodent models enable for bigger pattern sizes
and the technology of intensive information, which is key to establishing a broad
cjc 1295 ipamorelin security profile. Actual
Peptides ensures that our compounds, such as Semax Amidate
Peptide, are high-purity for constant leads to these sensitive
fashions. Researchers trying to answer what is cjc 1295 ipamorelin and totally understand
its effects make the most of a variety of laboratory fashions, every designed to isolate particular biological outcomes.
The choice of mannequin is determined by the research question,
shifting from easy cellular studies to complicated, living systems.
Potential benefits embody improved muscle restore, enhanced metabolism, physique composition assist, and
regenerative effects without direct hormone substitute.
Sermorelin’s major operate is to extend HGH production, nevertheless it does much more inside the physique.
As Soon As HGH ranges rise, the hormone stimulates cell regeneration, improves metabolism,
and helps tissue repair. This, in flip, results in improved muscle mass, higher pores and
skin elasticity, elevated power ranges, and enhanced general vitality.
Sermorelin remedy helps the body’s ability to rejuvenate itself by boosting natural
HGH production. It’s not a steroid, not a SARM, and never
synthetic progress hormone — it’s a selective peptide that works together with your body’s own rhythm to optimize GH ranges safely and constantly.
I’ve personally experienced sooner recovery instances between workouts since incorporating this peptide combination into my routine.
Athletes and bodybuilders I work with often report
noticeable enhancements in muscle fullness
and recovery instances within the first month of use.
Particular Person goals and medical steering should determine the choice between these peptides based mostly
on desired results and potential benefits.
For Ipamorelin, dosages normally range from a hundred to 300 mcg per dose, and it’s
often administered 2-3 times a day. It’s important to notice that these peptides should solely be used beneath the supervision of a medical professional,
as incorrect dosing can lead to potential
unwanted facet effects or lowered effectiveness. The purity of the research materials is an oblique
but crucial security consideration. An impure compound could lead to toxic cjc
1295 ipamorelin unwanted effects which may be mistakenly attributed to
the peptides themselves.
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The modular filter items may be personalized to particular buyer necessities, whether or not the oil quantity is 2 litres or 200,000 litres. Production that utilizes CJC® Fantastic Filters will experience lower cost of operation because of a decreased want for upkeep in addition to extending element lifetime. Particularly within the paper, steel, plastics and metal processing industries, as properly as in maritime purposes, there is a excessive risk of water entering the oil techniques due to the setting and processes involved. Grant Thornton Advisors LLC may use assets from its subsidiaries and home and/or international associates through the course of offering skilled providers to its shoppers. The CJC® Offline Oil Filtration system is an impartial unit run by a motor, a pump, and an oil filter, dependable for ensuring the longevity of applications using oil. Whether Or Not acute or steady water ingress — we give you the answer that’s exactly tailor-made to your utility and removes dissolved and emulsified water from your lubricant. Our fluid experts also can advise you on complex points — all the time with a focus on feasibility and cost-effectiveness.
With CJC® Offline Oil Filters installed, you ensure continuous clean and dry oil, elevated uptime, extended element and oil lifetime, resulting in savings in your maintenance prices. All of which leads to lowered environmental impression because of many litres of waste oil saved every year. Particles, water, oil degradation merchandise (Varnish, oxidation residues, etc.) and acids within the oil?
Apart from one Fangoria interview in 1990, Curry by no means publicly acknowledged his involvement in It till an interview with Moviefone in 2015, the place he referred to as the function of Pennywise “an exquisite part”. He rose to prominence as Dr. Frank-N-Furter in the musical movie The Rocky Horror Image Show (1975), reprising the role he had originated within the 1973 London, 1974 L A, and 1975 Broadway musical stage productions of The Rocky Horror Show. Grant Thornton LLP is a licensed impartial CPA firm that gives attest providers to its shoppers, and Grant Thornton Advisors LLC and its subsidiary entities present tax and business consulting services to their clients. Grant Thornton Advisors LLC and its subsidiary entities usually are not licensed CPA companies. If you imagine that a judge has a disability affecting his or her efficiency or has violated a quantity of of the Canons of the Code of Judicial Conduct, it is applicable to file a complaint with the CJC. Please describe as particularly as potential what the decide did or stated that causes you to believe she or he has a disability or has committed misconduct.
Do you have any questions about our merchandise, rental-purchase choices or oil care and fluid care? Is your oil or fluid exceptionally closely loaded and also you have no idea whether or not fluid or oil cleanliness can be improved? In 1989, A&M released One Of The Best of Tim Curry on CD and cassette, that includes songs from his albums (including a live version of “Alan”) and a previously unreleased music, a stay cover model of Bob Dylan’s “Easy Twist of Destiny”. Curry toured North America and some European international locations along with his band between 1978 and 1980. In 1990, Curry carried out because the Prosecutor in Roger Waters’ manufacturing of The Wall – Stay in Berlin.43 Though Curry’s first album was released in 1978, he had beforehand recorded a nine-track album for Lou Adler’s Ode Data in 1976. Nonetheless, the album remained unreleased in its entirety until February 2010, when it was made available as a authorized obtain entitled …From the Vaults (though four tracks from these classes had been launched on a 1990 Rocky Horror field set).
Discover your system and get in contact with us, so we are ready to help you in selecting an optimum resolution on your best long-term investment ever, via a professional partnership. On this page, the Jail Coverage Initiative has curated the entire analysis that we all know of concerning the circumstances of confinement in prisons and jails. For research on different felony justice matters, see our Research Library homepage. The El Paso County Sheriff’s Office was created in 1861, when El Paso County was formed as one of many 17 counties within the new Colorado Territory. Sheriff R. Scott Kelley was appointed Sheriff-the first of 29 men to carry that title over the subsequent 150+ years and laid the muse for an Office that at present sets the national normal in offering the greatest possible service to the residents. Our 541 sworn and 313 civilian workers are our best asset and ensure our mission is carried out each day. Our vision is to ensure El Paso County remains the most secure and most pleasant place to stay and visit within the state of Colorado.
We are dedicated to holding the very best normal for public safety to realize a county free of crime and public dysfunction. The CJC also has jurisdiction to investigate allegations that a decide has a bodily or psychological disability which affects the judge’s efficiency. You could both fill in and fax the CJC’s downloadable criticism kind or fax a letter to the CJC describing your grievance. If you wish to stay nameless, don’t present any private or contact info. On the complaint kind or in your letter, clarify, in your personal words and with as a lot detail as possible, the circumstances that led to your complaint and the information and evidence that you simply consider exist to help your criticism.
Our mission is to provide the residents of El Paso County efficient and efficient public safety providers. CJC® Fantastic Filters are best for controlling oil contamination ranges for particles, water, and degradation merchandise such as oxidation resin/sludge and varnish. Analysis reveals that 80% of oil associated failures and breakdowns are attributable to contaminated oil! Preventive oil upkeep is subsequently an important issue to ensure optimum tools reliability and avoid system breakdown. Curry’s third album, Simplicity, was released in 1981, again by A&M Records.41 This document, which didn’t promote in addition to the earlier choices, combined both original songs and canopy versions. One of Curry’s best-known tv roles is as Pennywise the Clown in the horror miniseries Stephen King’s It (1990).
The extraordinarily excessive filth holding capacity and filter efficiency make them to a greatest cost answer. CJC® Fine Filters deliver measurable buyer advantages, together with decrease operation and upkeep prices, elevated productiveness, and maximum lifetime for system parts, in-line filters, and oil. “It was only with the Desorber that the gear oil may lastly be dried satisfactorily. By avoiding the oil change, we had been capable of save EUR 4,890 (EUR 3.26/litre) – an essential contribution not solely when it comes to price range but in addition in phrases of useful resource financial savings. The glorious outcomes convinced us, so we determined to purchase two equivalent Desorbers for our tug boats, “Bugsier 5” and “Bugsier 6”. Info about wear particles, relative humidity, oil temperature, oxidation price and filter condition values is crucial for you to keep away from abrasive put on, cavitation, corrosion, viscosity modifications and lack of lubricating properties?
Our CJC® Oil Filters are recognised all over the world as being highly efficient. Summed up, CJC® Nice Filters offer highly efficient offline oil filtration options utilizing kidney loop filtration expertise that can assist lengthen oil change intervals, scale back CO₂ emissions, and save on upkeep costs. Depth filter inserts with application-specific filter materials, extraordinarily excessive dirt holding capacities and thus wonderful price-performance efficiency. Situation monitoring systems that provide you with precise oil condition values in real time – anytime, wherever.
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